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Estriol (E3) and estradiol (E2) are both forms of estrogen, but they serve different purposes. Estradiol is the strongest estrogen and is commonly used in systemic hormone therapy to help with symptoms like hot flashes and bone loss. Estriol is a gentler estrogen often used in vaginal creams to support vaginal dryness, tissue health, and urinary comfort during menopause. For localized vaginal symptoms, many women prefer estriol because it works directly on vaginal tissues with less systemic effect.

You will feel a difference usually in a few weeks, but typically it takes about 3 to 6 months of feeling optiminal resilience once your start BHRT.

All the ingredients in our creams are natural. There are no soy derived ingredients, parabens, or phenoxyethanol. The base of our P cream is organic wild yam and is paraben free, soy free, MSM free, EDTA free and fragrance free. In addition, the natural ingredient "wild yam extract" includes "USP progesterone" to help the body to convert wild yam extract into progesterone. If a P Cream does not include USP Progesterone listed, then you should avoid this cream as it won't convert to progesterone as needed by the body.

When you realize that there are thousands of receptor sites for progesterone throughout the body, you can begin to appreciate the powerful effects people can experience when they are given this hormone. There are at least 16 Benefits using P Cream. It is a hormone that is present in both sexes. It blocks the toxic effects of three hormones in the body - estradiol, insulin, and adrenaline.

A 2% cream is 20 mg. A 5% (50 mg per pump) is the exact, effective strength required to block adrenaline and insulin and the ideal strength to provide protection from excess estrogen. Lower strength progesterone cannot provide these benefits. In fact, using a 2% cream or less can actually stimulate estrogen receptor sites and cause unwanted side effects, or you would have to apply generously to obtain a higher dose throughout the day.

On rare occasions men and women can experience some side effects, but usually go away when you titrate down and gradually dose P Cream. Click herefor special considerations of using Progesterone Cream.

For progesterone to be effective, it needs to get into the bloodstream and avoid areas with fatty tissue, such as the abdomen and inner thighs. The ideal site for this is the forearm. For those people who have tension in the neck, tinnitus, or headaches, the back of the neck is an excellent site as well. View Video here.

Testing before supplementing hormones yields the most accurate information. Once you begin hormone therapy, interpreting test results becomes more complicated. Read our full article on the various testing applications i.e., serum, salvia and urine. Click here.